The 44-year-old Colon turned back the clock and dominated the defending World Series champions for seven innings, retiring his first 21 batters in an entertaining pitchers' duel with Astros ace Justin Verlander. Colon walked Carlos Correa on a 3-1 pitch to start the eighth before Josh Reddick lined an 0-2 delivery down the right-field line for a double that put runners at second and third.
Opposing fans in Houston gave Colon a standing ovation, and he clapped his bare hand softly against the outside of his glove. Two outs later, he was removed with the score tied at 1.
A fan favorite all around the majors, the beefy right-hander nicknamed "Big Sexy" is on his ninth team in his last 11 seasons.
Chirinos homered early for the only hit off Verlander, who struck out 11 over eight innings.
In the 10th, Chirinos hit a two-run double off Hector Rondon (1-1) that short-hopped the wall in straightaway center field. Jake Diekman pitched out of trouble in the bottom half for his first save.
Keone Kela (2-0) worked a scoreless ninth for the win.
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